This recognition will allow IMPACT access to state-of-the-art devices, reagents and operational expertise to implement a cellular manufacturing platform based on G-Rex®.
For the first time, the prestigious U.S. advanced therapy manufacturing company, Scale Ready, selects a Latin American institution for its G-Rex Fellowship Program, which seeks to support research and commercial centers working in preclinical research, process development or manufacturing of cell and gene therapies.
This recognition will enable IMPACT to access state-of-the-art devices, reagents and operational expertise to implement a G-Rex®-based cellular manufacturing platform. This will accelerate the development of gene and cell therapies, and optimizing existing processes to improve efficiency and reduce manufacturing costs under good manufacturing practice standards.
In detail, the contribution of G-Rex® will be used by the national center in its IMPACT chimeric antigen receptor T-cell therapy (CAR-T) research program during the parameter optimization stages and later in preclinical studies of antitumor activity, moving towards preclinical studies led by Soledad Mac-Keon, a postdoctoral researcher in the same group. The resulting data will provide the basis for the design of a proof-of-concept study in patients.
"This recognition reflects our commitment to the development of disruptive technologies in cell and gene therapy. Beyond technical transfer, our goal is to ensure that patients in Chile have access to advanced therapies, ensuring equal opportunities for all. This step brings us closer to our mission of transforming global health, always with the patient at the center," said Dr. Maroun Khoury, principal investigator of the proposal and director of IMPACT.
"ScaleReady is excited to support IMPACT with a G-Rex® grant to implement an efficient and cost-effective CAR-T manufacturing process. We look forward to collaborating with IMPACT to expand access to CAR-T treatments for patients in Chile," he said. John Wilson, CEO of Wilson Wolf Manufacturing Corporation and co-inventor of G-Rex®.
About the G-Rex® Scholarship Program
Launched by ScaleReady in collaboration with Wilson Wolf and CellReady, the program seeks to democratize access to advanced technologies by accelerating preclinical research, process development and manufacturing under quality standards.